Purified anti-human CD197 (CCR7) Antibody

產(chǎn)品類別：抗體
產(chǎn)品編號(hào)：353202
產(chǎn)品應(yīng)用：353202

規(guī)格

價(jià)格庫(kù)存

100µg

￥ 171 1

立即訂購(gòu)

訂購(gòu)熱線：021-34661276

收藏此商品

我要詢價(jià)

商品詳情
售后服務(wù)
相關(guān)文獻(xiàn)

Product Details

Verified Reactivity

Human

Reported Reactivity

African Green, Baboon, Cynomolgus, Rhesus

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

CCR7-transfected cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations

Dubrovsky L, et al. 2020. MBio. 11:. PubMed
Wagner J et al. 2019. Cell. 177(5):1330-1345 . PubMed
Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
Kondo H, et al. 2022. Front Immunol. 13:836923. PubMed
O'Boyle KC, et al. 2020. Methods Mol Biol. 2111:1. PubMed
Cobb DA, et al. 2022. J Immunother Cancer. 10:. PubMed
Del Alcazar D, et al. 2019. Cell Rep. 28:3047. PubMed
Li G, et al. 2022. Mol Ther Oncolytics. 24:887. PubMed
Mishra A, et al. 2021. Cell. 184(13):3394-3409.e20. PubMed
Schwabenland M, et al. 2021. Immunity. . PubMed
De Maeyer RPH, et al. 2020. Nat Immunol. 21:615. PubMed

RRID

AB_10945157 (BioLegend Cat. No. 353202)

Antigen Details

Structure: Chemokine receptor, G protein-coupled receptors (GPCR), seven transmembrane receptor.
Distribution: T cells, B cells, NK, dendritic cells.
Function: The chemokine receptor CCR7 plays a pivotal role in the homing of na?ve T cells and regulatory T cells to secondary lymphoid organs, and the migration of dendritic cells into afferent lymphatic vessels.
Ligand/Receptor: CCL19 and CCL21.
Cell Type: B cells, Dendritic cells, NK cells, T cells
Biology Area: Immunology
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Yanagihara S,　et al.　1998.　J. Immunol.　161:3096.
2. Charo IF,　et al.　2006.　N. Engl. J. Med.　354:610.
3. Reif K,　et al.　2002.　Nature　416:94.
4. Nakata B,　et al.　2008.　Oncology　74:69.
5.　Brodie T.　et al. 2013.　Cytometry A.　6: 530-2.　PubMed
6. Graves A.J. et al. 2014. Cytometry A. 7: 576–9　PubMed
7. Moncunill G. et al. 2014. Cytometry A. 12: 995-8　PubMed
Gene ID: 1236 View all products for this Gene ID
UniProt: View information about CD197 on UniProt.org