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PE anti-human CXCL10 (IP-10) Antibody

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Product Details

Verified Reactivity
Human
Reported Reactivity
Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. de Mingo Pulido , et al. 2021. Immunity. 54(6):1154-1167.e7. PubMed
  2. Wang Y, et al. 2021. Sci Rep. 1.429861111. PubMed
  3. Ferrando-Martinez S, et al. 2018. J Clin Invest. 128:2089. PubMed
RRID
AB_2561408 (BioLegend Cat. No. 519503) AB_2561409 (BioLegend Cat. No. 519504)

Antigen Details

Structure
CXC chemokine family, 8.7 kD
Distribution

Monocytes, endothelial cells, and fibroblasts

Function
Interacts with CXCR3 and serves as a chemoattractant for T cells, dendritic cells, monocytes/macrophages, and NK cells
Ligand/Receptor
CXCR3
Cell Type
B cells, Dendritic cells, Endothelial cells, Fibroblasts, Monocytes
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
Cytokines/Chemokines
Antigen References

1. Luster AD, et al. 1987. Proc. Natl. Acad. Sci. USA 84:2868. 
2. Kaplan G, et al. 1987. J. Exp. Med. 166:1098. 
3. Sarris AH, et al. 1993. J. Exp. Med. 178:1127.

Gene ID
3627 View all products for this Gene ID
UniProt
View information about CXCL10 on UniProt.org
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