Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse EBI3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2564303 (BioLegend Cat. No. 662602)
Antigen Details
- Structure
- 229 amino acids, predicted molecular weight of approximately 25 kD.
- Distribution
-
B cells, monocytes, and dendritic cells.
- Function
- Pro- and anti-inflammatory.
- Interaction
- IL-27 p28 subunit and IL-35 p35 subunit.
- Ligand/Receptor
- WSX-1(TCCR) and gp130.
- Cell Type
- B cells, Dendritic cells, Monocytes, Tregs
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Pflanz S, et al. 2002. Immunity 16:779.
2. Takeda A, et al. 2003. J. Immunol. 170:4886.
3. Pflanz S, et al. 2004. J. Immunol. 172:2225.
4. Li MF, et al. 2013. Dev. Comp. Immunol. 41:514.
5. Zeng JC, et al. 2013. Int. J. Clin. Exp. Pathol. 6:1806.
6. Ouyang H, et al. 2014. Am. J. Med. Sci. 348:156. - Gene ID
- 10148 View all products for this Gene ID
- UniProt
- View information about IL-27 IL-35 on UniProt.org
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