Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human M-CSF
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IP - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunoprecipitation. For immunoprecipitation, the suggested use of this reagent is 2-10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2564049 (BioLegend Cat. No. 661602)
Antigen Details
- Structure
- Three isoforms with 256-554 amino acids, predicted molecular weight of approximately 30-70 kD.
- Distribution
-
Cell membrane as a single-pass membrane protein. Processed macrophage colony-stimulating factor 1 is secreted into the extracellular space.
- Function
- Controls the production, differentiation, and function of macrophages.
- Interaction
- Disulfide-linked homodimer or heterodimer that interacts with CSF1R.
- Ligand/Receptor
- M-CSFR or CSF1R (CD115).
- Biology Area
- Cell Biology, Cell Proliferation and Viability, Immunology
- Molecular Family
- Cytokines/Chemokines, Growth Factors
- Antigen References
-
1. Kawasaki ES, et al. 1985. Science 230:291.
2. Wei S, et al. 2010. J. Leukoc. Biol. 88:495.
3. Hodge JM, et al. 2011. PloS One 6:e21462.
4. Morandi A, et al. 2011. PloS One 6:e27450.
5. Erblich B, et al. 2011. PloS One 6:e26317.
6. MacDonald KP, et al. 2010. Blood 116:3955. - Gene ID
- 1435 View all products for this Gene ID
- UniProt
- View information about M-CSF on UniProt.org
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