Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant full-length human Galectin-3.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IP - Verified - Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. For immunoprecipitation, the suggested use of this reagent is 1-5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
- AB_2565901 (BioLegend Cat. No. 677301) AB_2565902 (BioLegend Cat. No. 677302)
Antigen Details
- Structure
- 250 amino acids with a predicted molecular weight of approximately 26 kD.
- Distribution
-
Localized in the nucleus, cytoplasm, cell surface, or extracellular matrix. Expressed by tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells.
- Function
- Regulate cell proliferation, differentiation, adhesion, and anti-apoptosis.
- Interaction
- DMBT1, ITGA3, ITGB1, CSPG4, LGALS3BP, LYPD3, CYHR1, and UACA.
- Ligand/Receptor
- Variety of ligands such as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, CD66, and etc.
- Cell Type
- Dendritic cells
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Adhesion, Cell Biology, Cell Cycle/DNA Replication, Cell Motility/Cytoskeleton/Structure, Immunology, Signal Transduction, Transcription Factors
- Molecular Family
- Adhesion Molecules
- Antigen References
-
1. Kim HR, et al. 1999. Cancer Res. 16:4148.
2. Reljic R, et al. 2004. Immunol. Lett. 93:51.
3. Takenaka Y, et al. 2004. Mol. and Cell. Biol. 24:4395.
4. Joo HG, et al. 2001. J Leuko. Biol. 4:555.
5. Gudowska M, et al. 2014. Pol. Merkur. Lekarski. 37:348.
6. Xin M, et al. 2015. Biomed. Pharmacother. 69:179.
7. Filipe MD, et al. 2015. Clin. Chim. Acta. 443:48.
8. Funasaka T, et al. 2014. Glycobiology 24:886. - Gene ID
- 3958 View all products for this Gene ID
- UniProt
- View information about Mac-2 on UniProt.org
