Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Leptin.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
- AB_2565487 (BioLegend Cat. No. 675002)
Antigen Details
- Structure
- 167 amino acids with a predicted molecular weight of approximately 18 kD.
- Distribution
-
Secreted by adipocytes, gastric epithelial cells, or fibroblasts.
- Function
- Plays a major role in energy homeostasis and obesity.
- Interaction
- Interacts with Siglec-6.
- Ligand/Receptor
- Leptin receptors.
- Cell Type
- Epithelial cells, Fibroblasts
- Biology Area
- Angiogenesis, Cell Biology, Signal Transduction
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
1. Ando S, et al. 2014. Front Oncol. 4:340.
2. Upadhyay J, et al. 2015. Metabolism 64:105.
3. Sainz N, et al. 2015. Metabolism 64:35.
4. Zhang F, et al. 1997. Nature 387:206.
5. Brennan AM, et al. 2006. Nat. Clin. Pract. Endocrinol. Metab. 2:318.
6. Halaas JL, et al. 1995. Science 269:543. - Gene ID
- 3952 View all products for this Gene ID
- UniProt
- View information about Leptin on UniProt.org
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